Best Daycares in 29501 - Updated June 2026
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Discover the joy of early learning at La Petite Academy. Whether caring for your baby, preparing your preschooler for kindergarten, or supporting your elementary student (up to age 12) in the morning...
Infants
Families love the balance of nurturing care and milestone development in this program. In a warm, safe, stimulating classroom, children have a primary caregiver to attend to their needs. Plus, our exclusive, milestone-focused curriculum, Learn from the Start™, was developed by our educational experts to focus on key developmental milestones specific to infants. We emphasize each child’s development, rather than specific age, because all children grow and learn at their own pace, and in their own unique way. We’re also here when you need us. Ask your school about flexible enrollment options to fit your family’s schedule.
Toddlers
You’ll love the safe environment for exploration, excitement, and exercise we provide for your active child. Toddler classrooms also feature our milestone-focused curriculum, Learn from the Start™, focused on the key developmental milestones specific to this age group, with learning experiences designed to address the individual needs of each child, in each classroom.
Also offers: Twos, Drop-In Care
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Bright Futures Start Here! For 50 years, The Sunshine House has been helping children build a solid educational and social foundation -- with all the fun of childhood mixed in. Our curriculum nurtures...
Infants
We’ve created a warm, secure, and stimulating environment where your baby can grow, explore, and thrive! Our infant nursery is thoughtfully designed to provide comfort while encouraging curiosity and early learning. Your baby’s primary caregiver focuses on their individual needs, working with you to maintain a consistent routine that mirrors your home schedule—including bottle times, naps, and playtime. But here’s the best part—while your little one plays, they’re also learning! Our exclusive Brain Connect Infant Curriculum helps your baby reach key developmental milestones, from motor skills to language, cognitive growth, and emotional development.
Toddlers
From first steps to first friendships, our toddler childcare program nurtures your whole child—body, mind, and spirit—creating a joyful learning experience filled with exploration, play, and new discoveries. At this exciting stage, toddlers are full of curiosity, energy, and enthusiasm. Our program is designed to embrace this natural love of learning through fun, hands-on activities that introduce structure and routine while keeping the day engaging and playful!
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Charlie Brown Daycare and Preschool has served families in Florence for over 40 years. We are a small childcare and preschool setting for ages 6 weeks to 5 years (through 4K). We strive for a safe,...
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St. Anthony Catholic School Preschool provides early childhood education within a faith-based environment. The preschool program focuses on developing social, emotional, and academic skills through...
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Melissa Victoria Parker is a licensed child care center offering daycare programs located at 2916 Poinsett Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Melissa Johnson is a child care home offering daycare programs located in Florence, SC. Contact this provider to inquire about prices and availability.
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Precious One Learning Center is a licensed child care center offering daycare programs located at 1180 S Festival Drive in Florence, SC. Contact this provider to inquire about prices and availability.
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Kids First Learning Center is a licensed child care center offering daycare programs located at 3516 Southborough Rd in Florence, SC. Contact this provider to inquire about prices and availability.
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Risen Church Learning Center is a licensed child care center offering daycare programs located at 3700 W Lake Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Shealsea Robinson is a licensed child care center offering daycare programs located at 3786 W Pointe Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Gloria Christina Jones is a licensed child care center offering daycare programs located at 3625 Trotwood Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Ebenezer Weekday Ministry is a licensed child care center offering daycare programs located at 524 S Ebenezer Rd in Florence, SC. Contact this provider to inquire about prices and availability.
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Little Creations Learning Center is a licensed child care center offering daycare programs located at 3128 S Cashua Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Twana Durant is a licensed child care center offering daycare programs located at 607 McKeithan Rd in Florence, SC. Contact this provider to inquire about prices and availability.
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Melissa Johnson is a licensed child care center offering daycare programs located at 250 North Point in Florence, SC. Contact this provider to inquire about prices and availability.
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Trinity Early Head Start Center is a licensed child care center offering daycare programs located at 124 W Darlington St in Florence, SC. Contact this provider to inquire about prices and...
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Montessori School of Florence is a licensed child care center offering daycare programs located at 510 W Palmetto St in Florence, SC. Contact this provider to inquire about prices and availability.
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Angels Inn is a licensed child care center offering daycare programs located at 2030 N Cashua Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Tinker Bell Nursery & Day Care is a licensed child care center offering daycare programs located at 1255 W Sumter St in Florence, SC. Contact this provider to inquire about prices and availability.
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Coquette W Ross is a licensed child care center offering daycare programs located at 3042 Meadowbrook Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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First Presbyterian Child Development Center is a licensed child care center offering daycare programs located at 700 S Park Ave in Florence, SC. Contact this provider to inquire about prices and...
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Maranatha Christian School is a licensed child care center offering daycare programs located at 2624 W Palmetto St in Florence, SC. Contact this provider to inquire about prices and availability.
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Little Luvbugs Childcare Center is a licensed child care center offering daycare programs located at 1501 W Palmetto St in Florence, SC. Contact this provider to inquire about prices and availability.
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Marybell Velasquez-Scott is a licensed child care center offering daycare programs located at 1131 Pineapple Gate Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Shirley Lockett is a licensed child care center offering daycare programs located at 1305 W Sumter St in Florence, SC. Contact this provider to inquire about prices and availability.
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Heather Gardner is a licensed child care center offering daycare programs located at 172 State Rd S-21-332 in Florence, SC. Contact this provider to inquire about prices and availability.
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All Saints Episcopal Day School is a licensed child care center offering daycare programs located at 1425 Cherokee Rd in Florence, SC. Contact this provider to inquire about prices and availability.
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Convenient Childcare is a licensed child care center offering daycare programs located at 1210 S Cashua Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Deborah Dubose Jett is a licensed child care center offering daycare programs located at 612 Indian River Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Kingdom Kids Learning Center is a licensed child care center offering daycare programs located at 822 S Cashua Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Murray Gregg Pierce is a licensed child care center offering daycare programs located at 2017 N Tobin Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Bernetra Boyd-Nowline is a licensed child care center offering daycare programs located at 1021 Harmony St in Florence, SC. Contact this provider to inquire about prices and availability.
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Small Beginnings Childcare Center is a licensed child care center offering daycare programs located at 1751 W King Ave in Florence, SC. Contact this provider to inquire about prices and availability.
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Tanzania Jones-Coley is a licensed child care center offering daycare programs located at 2210 W Sumter St in Florence, SC. Contact this provider to inquire about prices and availability.
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Catherine Wilson is a licensed child care center offering daycare programs located at 616 W Sumter St in Florence, SC. Contact this provider to inquire about prices and availability.
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Melanie Pierce-Greer is a licensed child care center offering daycare programs located at 1790 Lake Wateree Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Lakiesta Davis is a licensed child care center offering daycare programs located at 1627 Gregg Ave a3 in Florence, SC. Contact this provider to inquire about prices and availability.
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Barbara Cherry is a licensed child care center offering daycare programs located at 2951 Palmetto Heights Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Jayleel Waiters is a licensed child care center offering daycare programs located at 110 N Homestead Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Chrysalis Center is a licensed child care center offering daycare programs located at 1430 S Cashua Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Cradle To Crayons Day Care Center is a licensed child care center offering daycare programs located at 3900 Pine Needles Rd in Florence, SC. Contact this provider to inquire about prices and...
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Thursday's Child is a licensed child care center offering daycare programs located at 1804 2nd Loop Rd in Florence, SC. Contact this provider to inquire about prices and availability.
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Candace Pompey is a child care home offering daycare programs located in Florence, SC. Contact this provider to inquire about prices and availability.
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Jayleel Waiters is a child care home offering daycare programs located in Florence, SC. Contact this provider to inquire about prices and availability.
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The Byrd's Nest Daycare is a licensed child care center offering daycare programs located in Florence, SC. Contact this provider to inquire about prices and availability.
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Melanie Pierce-Greer is a child care home offering daycare programs located in Florence, SC. Contact this provider to inquire about prices and availability.
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Saint Paul Children's Learning Center is a licensed child care center offering daycare programs located at 1629 W Palmetto St in Florence, SC. Contact this provider to inquire about prices and...
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Royall Elementary School is a license exempt child care center offering daycare programs located at 1101 Cheraw Dr in Florence, SC. Contact this provider to inquire about prices and availability.
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Guides
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Exploring Childcare Costs in South Carolina
Curious how much daycare or preschool really costs in South Carolina? We break down average childcare rates by city, age, and program type—based on real data from local providers.
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How to Find & Apply for Childcare Assistance in South Carolina
Explore financial assistance programs available in South Carolina, including childcare subsidies, tax credits, and free preschool options for eligible families.
FAQs About Florence Daycares
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How many daycare providers are in Florence?
- There are currently 115 daycare providers in Florence. This includes full-time, part-time, and home daycare providers.